Delete a pattern and every associated hypotheses from the dataset

delete.pattern(x, pattern)

Arguments

x

A TRONCO compliant dataset.

pattern

A pattern name

Value

A TRONCO complian dataset.

Examples

data(test_dataset)
delete.pattern(test_dataset, pattern='XOR_EZH2')
#> $genotypes
#>            gene 4 gene 5 gene 7 gene 29 gene 30 gene 31 gene 32 gene 33 gene 34
#> patient 1       0      0      0       1       0       0       0       0       0
#> patient 2       0      0      0       1       0       0       0       0       1
#> patient 3       0      0      0       1       1       0       0       0       0
#> patient 4       0      0      0       1       0       0       0       0       1
#> patient 5       0      0      0       1       0       0       0       0       0
#> patient 6       0      0      0       1       0       0       0       0       0
#> patient 7       0      0      0       1       0       0       0       0       0
#> patient 8       0      0      0       1       0       0       0       0       0
#> patient 9       0      0      1       1       0       0       0       0       0
#> patient 10      0      0      0       1       0       0       0       0       0
#> patient 11      0      0      0       1       0       0       0       0       0
#> patient 12      0      0      0       1       1       0       0       0       0
#> patient 13      0      0      0       1       0       0       0       0       0
#> patient 14      0      0      0       1       0       0       0       0       0
#> patient 15      0      0      0       0       0       0       0       0       0
#> patient 16      0      0      0       0       0       0       0       0       0
#> patient 17      0      0      0       0       1       0       0       1       0
#> patient 18      0      0      0       0       0       0       0       0       0
#> patient 19      0      0      0       0       0       0       0       0       0
#> patient 20      0      0      0       0       0       0       0       1       0
#> patient 21      0      0      1       0       0       0       1       0       0
#> patient 22      0      0      0       0       0       0       0       0       0
#> patient 23      1      0      0       0       0       0       0       1       0
#> patient 24      1      0      1       0       0       0       0       1       1
#> patient 25      1      0      0       0       0       0       0       0       0
#> patient 26      0      0      0       0       0       0       0       0       0
#> patient 27      0      1      1       0       0       0       1       0       0
#> patient 28      0      0      0       0       0       0       0       0       0
#> patient 29      0      0      1       0       0       0       0       1       0
#> patient 30      0      0      0       0       0       0       0       0       0
#> patient 31      0      0      0       0       0       0       0       0       0
#> patient 32      0      0      1       0       0       1       0       0       0
#> patient 33      0      0      0       0       0       0       0       0       0
#> patient 34      0      0      0       0       0       0       1       0       0
#> patient 35      0      0      0       0       0       0       0       0       0
#> patient 36      0      0      0       0       0       0       0       0       0
#> patient 37      0      0      0       0       0       0       0       0       0
#> patient 38      0      0      0       0       0       0       0       1       0
#> patient 39      0      0      1       0       0       0       0       0       0
#> patient 40      0      0      0       0       0       0       0       0       0
#>            gene 36 gene 40 gene 44 gene 47 gene 49 gene 50 gene 51 gene 52
#> patient 1        0       0       0       0       0       0       0       0
#> patient 2        0       0       0       0       0       0       0       0
#> patient 3        0       0       0       0       0       0       0       0
#> patient 4        0       0       0       0       0       0       0       0
#> patient 5        0       0       0       0       0       0       0       0
#> patient 6        0       0       0       0       0       0       0       0
#> patient 7        0       0       0       0       0       1       0       0
#> patient 8        0       0       0       0       0       0       0       0
#> patient 9        0       0       0       0       0       0       0       0
#> patient 10       0       0       0       0       0       0       0       0
#> patient 11       0       0       0       0       0       0       0       0
#> patient 12       0       0       1       0       0       0       0       0
#> patient 13       0       0       0       0       0       0       0       0
#> patient 14       0       0       0       0       0       0       0       0
#> patient 15       1       0       0       0       0       0       0       0
#> patient 16       0       0       0       0       0       0       0       0
#> patient 17       0       0       0       0       0       0       0       0
#> patient 18       0       0       0       0       0       0       0       0
#> patient 19       0       0       0       0       0       0       0       1
#> patient 20       0       0       0       0       0       0       1       0
#> patient 21       0       0       0       0       0       0       0       0
#> patient 22       0       1       0       0       0       0       0       0
#> patient 23       0       0       0       0       0       0       0       0
#> patient 24       0       0       0       0       0       0       0       0
#> patient 25       0       0       0       0       0       0       0       0
#> patient 26       0       0       0       0       0       0       0       0
#> patient 27       0       0       0       0       0       0       0       0
#> patient 28       0       0       0       0       0       0       0       0
#> patient 29       0       0       0       0       0       0       0       0
#> patient 30       0       0       0       0       0       0       0       0
#> patient 31       0       0       0       1       0       0       0       0
#> patient 32       0       0       0       0       0       0       0       0
#> patient 33       0       0       0       0       0       0       0       0
#> patient 34       0       0       0       0       0       0       0       0
#> patient 35       0       0       0       0       0       0       0       0
#> patient 36       0       0       0       0       0       0       0       0
#> patient 37       0       0       0       0       0       0       0       0
#> patient 38       0       0       0       0       1       0       0       0
#> patient 39       0       0       0       0       0       0       0       0
#> patient 40       0       0       0       0       0       0       0       0
#>            gene 53 gene 54 gene 55 gene 56 gene 66 gene 69 gene 77 gene 88
#> patient 1        0       0       0       0       0       0       0       0
#> patient 2        0       0       0       0       0       0       0       0
#> patient 3        0       0       0       0       0       0       0       0
#> patient 4        0       0       0       0       0       0       0       0
#> patient 5        0       0       1       0       0       0       0       0
#> patient 6        0       0       0       0       0       0       0       0
#> patient 7        0       0       0       0       0       0       0       0
#> patient 8        0       0       0       0       0       0       0       0
#> patient 9        0       0       0       0       0       0       0       0
#> patient 10       0       0       0       0       0       0       0       0
#> patient 11       0       0       0       0       0       0       0       0
#> patient 12       0       0       0       0       0       0       0       1
#> patient 13       0       0       1       0       0       0       0       1
#> patient 14       0       0       0       0       0       0       0       0
#> patient 15       0       0       0       0       0       0       0       0
#> patient 16       0       1       0       0       0       0       0       0
#> patient 17       1       0       0       0       0       0       0       0
#> patient 18       0       0       0       0       0       0       0       0
#> patient 19       0       0       0       0       0       0       0       0
#> patient 20       0       0       0       0       0       0       0       0
#> patient 21       0       0       0       0       0       0       0       0
#> patient 22       0       0       0       0       0       0       0       0
#> patient 23       0       0       0       1       0       0       0       0
#> patient 24       0       0       0       0       0       0       0       0
#> patient 25       0       0       0       1       0       1       0       0
#> patient 26       0       0       0       0       0       0       0       1
#> patient 27       0       0       0       0       0       0       0       0
#> patient 28       0       0       0       0       0       0       0       0
#> patient 29       0       0       0       0       0       0       0       1
#> patient 30       0       0       1       0       0       0       0       0
#> patient 31       0       0       0       0       0       0       1       0
#> patient 32       0       0       0       0       0       0       0       0
#> patient 33       0       0       0       0       0       0       0       0
#> patient 34       0       0       1       0       1       0       1       0
#> patient 35       0       0       0       0       0       0       0       0
#> patient 36       0       0       0       0       0       0       0       0
#> patient 37       0       0       0       0       0       0       0       0
#> patient 38       0       0       0       0       0       0       0       0
#> patient 39       0       0       0       0       0       0       0       0
#> patient 40       0       0       0       0       0       0       0       1
#>            gene 89 gene 91 gene 111 OR_CSF3R
#> patient 1        0       0        0        0
#> patient 2        0       1        0        0
#> patient 3        0       0        0        0
#> patient 4        0       1        0        0
#> patient 5        0       0        1        1
#> patient 6        1       0        0        0
#> patient 7        0       1        0        0
#> patient 8        0       1        0        0
#> patient 9        0       0        0        0
#> patient 10       0       0        0        0
#> patient 11       0       0        0        0
#> patient 12       0       0        0        0
#> patient 13       0       0        0        1
#> patient 14       0       0        1        1
#> patient 15       0       0        0        0
#> patient 16       0       0        0        0
#> patient 17       0       0        0        0
#> patient 18       0       0        0        0
#> patient 19       0       0        0        0
#> patient 20       0       0        0        0
#> patient 21       0       0        0        0
#> patient 22       0       0        0        0
#> patient 23       0       0        0        0
#> patient 24       0       0        0        0
#> patient 25       0       0        0        0
#> patient 26       0       0        0        0
#> patient 27       0       0        0        0
#> patient 28       0       0        0        0
#> patient 29       0       0        0        0
#> patient 30       0       0        0        1
#> patient 31       0       0        0        0
#> patient 32       0       0        0        0
#> patient 33       0       0        0        0
#> patient 34       0       0        0        1
#> patient 35       0       0        1        1
#> patient 36       0       0        0        0
#> patient 37       0       0        0        0
#> patient 38       0       0        0        0
#> patient 39       0       0        0        0
#> patient 40       0       0        0        0
#> 
#> $annotations
#>          type                       event           
#> gene 4   "ins_del"                  "TET2"          
#> gene 5   "ins_del"                  "EZH2"          
#> gene 7   "ins_del"                  "ASXL1"         
#> gene 29  "missense_point_mutations" "SETBP1"        
#> gene 30  "missense_point_mutations" "NRAS_Ex2_3"    
#> gene 31  "missense_point_mutations" "KRAS_Ex2_3"    
#> gene 32  "missense_point_mutations" "TET2"          
#> gene 33  "missense_point_mutations" "EZH2"          
#> gene 34  "missense_point_mutations" "CBL_Ex_8_9"    
#> gene 36  "missense_point_mutations" "IDH2_R140"     
#> gene 40  "missense_point_mutations" "SF3B1_Ex_12_15"
#> gene 44  "missense_point_mutations" "JARID_2_Ex1_18"
#> gene 47  "missense_point_mutations" "EED_Ex2_12"    
#> gene 49  "missense_point_mutations" "CEBPA"         
#> gene 50  "missense_point_mutations" "EPHB3"         
#> gene 51  "missense_point_mutations" "ETNK1"         
#> gene 52  "missense_point_mutations" "GATA2"         
#> gene 53  "missense_point_mutations" "IRAK4"         
#> gene 54  "missense_point_mutations" "MTA2"          
#> gene 55  "missense_point_mutations" "CSF3R"         
#> gene 56  "missense_point_mutations" "KIT"           
#> gene 66  "nonsense_ins_del"         "WT1"           
#> gene 69  "nonsense_ins_del"         "RUNX_1"        
#> gene 77  "nonsense_ins_del"         "CEBPA"         
#> gene 88  "nonsense_point_mutations" "TET2"          
#> gene 89  "nonsense_point_mutations" "EZH2"          
#> gene 91  "nonsense_point_mutations" "ASXL1"         
#> gene 111 "nonsense_point_mutations" "CSF3R"         
#> OR_CSF3R "Pattern"                  "OR_CSF3R"      
#> 
#> $types
#>                          color           
#> ins_del                  "khaki"         
#> missense_point_mutations "lightgreen"    
#> nonsense_ins_del         "cornflowerblue"
#> nonsense_point_mutations "firebrick1"    
#> Pattern                  "slateblue"     
#> 
#> $stages
#> [1] NA
#> 
#> $hypotheses
#> $hypotheses$num.hypotheses
#> [1] 1
#> 
#> $hypotheses$hlist
#>       cause      effect    
#>  [1,] "OR_CSF3R" "gene 4"  
#>  [2,] "OR_CSF3R" "gene 5"  
#>  [3,] "OR_CSF3R" "gene 7"  
#>  [4,] "OR_CSF3R" "gene 29" 
#>  [5,] "OR_CSF3R" "gene 30" 
#>  [6,] "OR_CSF3R" "gene 31" 
#>  [7,] "OR_CSF3R" "gene 32" 
#>  [8,] "OR_CSF3R" "gene 33" 
#>  [9,] "OR_CSF3R" "gene 34" 
#> [10,] "OR_CSF3R" "gene 36" 
#> [11,] "OR_CSF3R" "gene 40" 
#> [12,] "OR_CSF3R" "gene 44" 
#> [13,] "OR_CSF3R" "gene 47" 
#> [14,] "OR_CSF3R" "gene 49" 
#> [15,] "OR_CSF3R" "gene 50" 
#> [16,] "OR_CSF3R" "gene 51" 
#> [17,] "OR_CSF3R" "gene 52" 
#> [18,] "OR_CSF3R" "gene 53" 
#> [19,] "OR_CSF3R" "gene 54" 
#> [20,] "OR_CSF3R" "gene 56" 
#> [21,] "OR_CSF3R" "gene 66" 
#> [22,] "OR_CSF3R" "gene 69" 
#> [23,] "OR_CSF3R" "gene 77" 
#> [24,] "OR_CSF3R" "gene 88" 
#> [25,] "OR_CSF3R" "gene 89" 
#> [26,] "OR_CSF3R" "gene 91" 
#> [27,] "gene 4"   "OR_CSF3R"
#> [28,] "gene 5"   "OR_CSF3R"
#> [29,] "gene 7"   "OR_CSF3R"
#> [30,] "gene 29"  "OR_CSF3R"
#> [31,] "gene 30"  "OR_CSF3R"
#> [32,] "gene 31"  "OR_CSF3R"
#> [33,] "gene 32"  "OR_CSF3R"
#> [34,] "gene 33"  "OR_CSF3R"
#> [35,] "gene 34"  "OR_CSF3R"
#> [36,] "gene 36"  "OR_CSF3R"
#> [37,] "gene 40"  "OR_CSF3R"
#> [38,] "gene 44"  "OR_CSF3R"
#> [39,] "gene 47"  "OR_CSF3R"
#> [40,] "gene 49"  "OR_CSF3R"
#> [41,] "gene 50"  "OR_CSF3R"
#> [42,] "gene 51"  "OR_CSF3R"
#> [43,] "gene 52"  "OR_CSF3R"
#> [44,] "gene 53"  "OR_CSF3R"
#> [45,] "gene 54"  "OR_CSF3R"
#> [46,] "gene 56"  "OR_CSF3R"
#> [47,] "gene 66"  "OR_CSF3R"
#> [48,] "gene 69"  "OR_CSF3R"
#> [49,] "gene 77"  "OR_CSF3R"
#> [50,] "gene 88"  "OR_CSF3R"
#> [51,] "gene 89"  "OR_CSF3R"
#> [52,] "gene 91"  "OR_CSF3R"
#> 
#> $hypotheses$hstructure
#> $hypotheses$hstructure$OR_CSF3R
#>                     gene 55 gene 111 OR_gene 55_gene 111
#> gene 55                   0        0                   1
#> gene 111                  0        0                   1
#> OR_gene 55_gene 111       0        0                   0
#> 
#> 
#> $hypotheses$patterns
#> $hypotheses$patterns$OR_CSF3R
#> [1] "gene 55"  "gene 111"
#> 
#> 
#> $hypotheses$atoms
#> $hypotheses$atoms$`gene 4`
#> NULL
#> 
#> $hypotheses$atoms$`gene 7`
#> NULL
#> 
#> $hypotheses$atoms$`gene 29`
#> NULL
#> 
#> $hypotheses$atoms$`gene 30`
#> NULL
#> 
#> $hypotheses$atoms$`gene 31`
#> NULL
#> 
#> $hypotheses$atoms$`gene 32`
#> NULL
#> 
#> $hypotheses$atoms$`gene 34`
#> NULL
#> 
#> $hypotheses$atoms$`gene 36`
#> NULL
#> 
#> $hypotheses$atoms$`gene 40`
#> NULL
#> 
#> $hypotheses$atoms$`gene 44`
#> NULL
#> 
#> $hypotheses$atoms$`gene 47`
#> NULL
#> 
#> $hypotheses$atoms$`gene 49`
#> NULL
#> 
#> $hypotheses$atoms$`gene 50`
#> NULL
#> 
#> $hypotheses$atoms$`gene 51`
#> NULL
#> 
#> $hypotheses$atoms$`gene 52`
#> NULL
#> 
#> $hypotheses$atoms$`gene 53`
#> NULL
#> 
#> $hypotheses$atoms$`gene 54`
#> NULL
#> 
#> $hypotheses$atoms$`gene 55`
#> [1] "OR_CSF3R"
#> 
#> $hypotheses$atoms$`gene 56`
#> NULL
#> 
#> $hypotheses$atoms$`gene 66`
#> NULL
#> 
#> $hypotheses$atoms$`gene 69`
#> NULL
#> 
#> $hypotheses$atoms$`gene 77`
#> NULL
#> 
#> $hypotheses$atoms$`gene 88`
#> NULL
#> 
#> $hypotheses$atoms$`gene 91`
#> NULL
#> 
#> $hypotheses$atoms$`gene 111`
#> [1] "OR_CSF3R"
#> 
#> 
#>